Multiple Rad52-Mediated Homology-Directed Repair Mechanisms Are Required to Prevent Telomere Attrition-Induced Senescence in Saccharomyces cerevisiae

Most human somatic cells express insufficient levels of telomerase, which can result in telomere shortening and eventually senescence, both of which are hallmarks of ageing. Homology-directed repair (HDR) is important for maintaining proper telomere function in yeast and mammals. In Saccharomyces ce...

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Detalles Bibliográficos
Autores principales: Claussin, Clémence, Chang, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948829/
https://www.ncbi.nlm.nih.gov/pubmed/27428329
http://dx.doi.org/10.1371/journal.pgen.1006176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948829/
https://www.ncbi.nlm.nih.gov/pubmed/27428329
http://dx.doi.org/10.1371/journal.pgen.1006176

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