Inflammatory Stress Sensitizes the Liver to Atorvastatin-Induced Injury in ApoE-/- Mice

Statins, which are revolutionized cholesterol-lowing agents, have been reported to have unfavorable effects on the liver. Inflammatory stress is a susceptibility factor for drug-induced liver injury. This study investigated whether inflammatory stress sensitized the liver to statin-induced toxicity...

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Detalles Bibliográficos
Autores principales: Wu, Wei, Zhao, Lei, Yang, Ping, Zhou, Wei, Li, Beibei, Moorhead, John F., Varghese, Zac, Ruan, Xiong Z., Chen, Yaxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948878/
https://www.ncbi.nlm.nih.gov/pubmed/27428373
http://dx.doi.org/10.1371/journal.pone.0159512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948878/
https://www.ncbi.nlm.nih.gov/pubmed/27428373
http://dx.doi.org/10.1371/journal.pone.0159512

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