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Proteasome Inhibition Contributed to the Cytotoxicity of Arenobufagin after Its Binding with Na, K-ATPase in Human Cervical Carcinoma HeLa Cells

Although the possibility of developing cardiac steroids/cardiac glycosides as novel cancer therapeutic agents has been recognized, the mechanism of their anticancer activity is still not clear enough. Toad venom extract containing bufadienolides, which belong to cardiac steroids, has actually long b...

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Detalles Bibliográficos
Autores principales: Yue, Qingxi, Zhen, Hong, Huang, Ming, Zheng, Xi, Feng, Lixing, Jiang, Baohong, Yang, Min, Wu, Wanying, Liu, Xuan, Guo, Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948917/
https://www.ncbi.nlm.nih.gov/pubmed/27428326
http://dx.doi.org/10.1371/journal.pone.0159034