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Proteasome Inhibition Contributed to the Cytotoxicity of Arenobufagin after Its Binding with Na, K-ATPase in Human Cervical Carcinoma HeLa Cells
Although the possibility of developing cardiac steroids/cardiac glycosides as novel cancer therapeutic agents has been recognized, the mechanism of their anticancer activity is still not clear enough. Toad venom extract containing bufadienolides, which belong to cardiac steroids, has actually long b...
Autores principales: | Yue, Qingxi, Zhen, Hong, Huang, Ming, Zheng, Xi, Feng, Lixing, Jiang, Baohong, Yang, Min, Wu, Wanying, Liu, Xuan, Guo, Dean |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948917/ https://www.ncbi.nlm.nih.gov/pubmed/27428326 http://dx.doi.org/10.1371/journal.pone.0159034 |
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