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Lipoprotein(a) and vitamin C impair development of breast cancer tumors in Lp(a)+; Gulo(−/−) mice

Cancer progression is characterized by loss of extracellular matrix (ECM) integrity, which is a precondition for tumor growth and metastasis. In order to elucidate the precise mechanisms of ECM degradation in cancer we used a genetically modified mouse mimicking two distinct human metabolic features...

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Detalles Bibliográficos
Autores principales: Cha, John, Roomi, M. Waheed, Kalinovsky, Tatiana, Niedzwiecki, Aleksandra, Rath, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948959/
https://www.ncbi.nlm.nih.gov/pubmed/27573077
http://dx.doi.org/10.3892/ijo.2016.3597