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Lipoprotein(a) and vitamin C impair development of breast cancer tumors in Lp(a)+; Gulo(−/−) mice
Cancer progression is characterized by loss of extracellular matrix (ECM) integrity, which is a precondition for tumor growth and metastasis. In order to elucidate the precise mechanisms of ECM degradation in cancer we used a genetically modified mouse mimicking two distinct human metabolic features...
Autores principales: | Cha, John, Roomi, M. Waheed, Kalinovsky, Tatiana, Niedzwiecki, Aleksandra, Rath, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948959/ https://www.ncbi.nlm.nih.gov/pubmed/27573077 http://dx.doi.org/10.3892/ijo.2016.3597 |
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