CYP2D6 function moderates the pharmacokinetics and pharmacodynamics of 3,4-methylene-dioxymethamphetamine in a controlled study in healthy individuals

The role of genetic polymorphisms in cytochrome (CYP) 2D6 involved in the metabolism of 3,4-methylene-dioxymethamphetamine (MDMA, ecstasy) is unclear. Effects of genetic variants in CYP2D6 on the pharmacokinetics and pharmacodynamic effects of MDMA were characterized in 139 healthy individuals (70 m...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmid, Yasmin, Vizeli, Patrick, Hysek, Cédric M., Prestin, Katharina, Meyer zu Schwabedissen, Henriette E., Liechti, Matthias E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949007/
https://www.ncbi.nlm.nih.gov/pubmed/27253829
http://dx.doi.org/10.1097/FPC.0000000000000231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949007/
https://www.ncbi.nlm.nih.gov/pubmed/27253829
http://dx.doi.org/10.1097/FPC.0000000000000231

Ejemplares similares