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A Single-Dose, Open-Label Study of the Pharmacokinetics, Safety, and Tolerability of Lisdexamfetamine Dimesylate in Individuals With Normal and Impaired Renal Function

BACKGROUND: Lisdexamfetamine (LDX) and d-amphetamine pharmacokinetics were assessed in individuals with normal and impaired renal function after a single LDX dose; LDX and d-amphetamine dialyzability was also examined. METHODS: Adults (N = 40; 8/group) were enrolled in 1 of 5 renal function groups [...

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Detalles Bibliográficos
Autores principales: Ermer, James, Corcoran, Mary, Lasseter, Kenneth, Marbury, Thomas, Yan, Brian, Martin, Patrick T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Therapeutic Drug Monitoring 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949011/
https://www.ncbi.nlm.nih.gov/pubmed/26926668
http://dx.doi.org/10.1097/FTD.0000000000000296