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Sepsis modeling in mice: ligation length is a major severity factor in cecal ligation and puncture

BACKGROUND: The cecal ligation and puncture (CLP) model, a gold standard in sepsis research, is associated with an important variability in mortality. While the number of punctures and needle size is well described in CLP animal studies, the length of cecal ligation is often not. The relationship be...

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Detalles Bibliográficos
Autores principales: Ruiz, Stéphanie, Vardon-Bounes, Fanny, Merlet-Dupuy, Virginie, Conil, Jean-Marie, Buléon, Marie, Fourcade, Olivier, Tack, Ivan, Minville, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949182/
https://www.ncbi.nlm.nih.gov/pubmed/27430881
http://dx.doi.org/10.1186/s40635-016-0096-z