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Sepsis modeling in mice: ligation length is a major severity factor in cecal ligation and puncture
BACKGROUND: The cecal ligation and puncture (CLP) model, a gold standard in sepsis research, is associated with an important variability in mortality. While the number of punctures and needle size is well described in CLP animal studies, the length of cecal ligation is often not. The relationship be...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949182/ https://www.ncbi.nlm.nih.gov/pubmed/27430881 http://dx.doi.org/10.1186/s40635-016-0096-z |