The C2H2-ZF transcription factor Zfp335 recognizes two consensus motifs using separate zinc finger arrays

The complexities of DNA recognition by transcription factors (TFs) with multiple Cys2–His2 zinc fingers (C2H2-ZFs) remain poorly studied. We previously reported a mutation (R1092W) in the C2H2-ZF TF Zfp335 that led to selective loss of binding at a subset of targets, although the basis for this effe...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Brenda Yuyuan, Foo, Chuan-Sheng, Wu, Shuang, Cyster, Jason G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949324/
https://www.ncbi.nlm.nih.gov/pubmed/27401554
http://dx.doi.org/10.1101/gad.279406.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949324/
https://www.ncbi.nlm.nih.gov/pubmed/27401554
http://dx.doi.org/10.1101/gad.279406.116

Ejemplares similares