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The C2H2-ZF transcription factor Zfp335 recognizes two consensus motifs using separate zinc finger arrays
The complexities of DNA recognition by transcription factors (TFs) with multiple Cys2–His2 zinc fingers (C2H2-ZFs) remain poorly studied. We previously reported a mutation (R1092W) in the C2H2-ZF TF Zfp335 that led to selective loss of binding at a subset of targets, although the basis for this effe...
Autores principales: | Han, Brenda Yuyuan, Foo, Chuan-Sheng, Wu, Shuang, Cyster, Jason G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949324/ https://www.ncbi.nlm.nih.gov/pubmed/27401554 http://dx.doi.org/10.1101/gad.279406.116 |
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