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A microRNA program in the C. elegans hypodermis couples to intestinal mTORC2/PQM-1 signaling to modulate fat transport

Animals integrate metabolic, developmental, and environmental information before committing key resources to reproduction. In Caenorhabditis elegans, adult animals transport fat from intestinal cells to the germline to promote reproduction. We identified a microRNA (miRNA)-regulated developmental ti...

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Detalles Bibliográficos
Autores principales: Dowen, Robert H., Breen, Peter C., Tullius, Thomas, Conery, Annie L., Ruvkun, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949325/
https://www.ncbi.nlm.nih.gov/pubmed/27401555
http://dx.doi.org/10.1101/gad.283895.116