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A microRNA program in the C. elegans hypodermis couples to intestinal mTORC2/PQM-1 signaling to modulate fat transport
Animals integrate metabolic, developmental, and environmental information before committing key resources to reproduction. In Caenorhabditis elegans, adult animals transport fat from intestinal cells to the germline to promote reproduction. We identified a microRNA (miRNA)-regulated developmental ti...
Autores principales: | Dowen, Robert H., Breen, Peter C., Tullius, Thomas, Conery, Annie L., Ruvkun, Gary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949325/ https://www.ncbi.nlm.nih.gov/pubmed/27401555 http://dx.doi.org/10.1101/gad.283895.116 |
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