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HGF-independent regulation of MET and GAB1 by nonreceptor tyrosine kinase FER potentiates metastasis in ovarian cancer

Ovarian cancer cells disseminate readily within the peritoneal cavity, which promotes metastasis, and are often resistant to chemotherapy. Ovarian cancer patients tend to present with advanced disease, which also limits treatment options; consequently, new therapies are required. The oncoprotein tyr...

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Detalles Bibliográficos
Autores principales: Fan, Gaofeng, Zhang, Siwei, Gao, Yan, Greer, Peter A., Tonks, Nicholas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949327/
https://www.ncbi.nlm.nih.gov/pubmed/27401557
http://dx.doi.org/10.1101/gad.284166.116