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HGF-independent regulation of MET and GAB1 by nonreceptor tyrosine kinase FER potentiates metastasis in ovarian cancer
Ovarian cancer cells disseminate readily within the peritoneal cavity, which promotes metastasis, and are often resistant to chemotherapy. Ovarian cancer patients tend to present with advanced disease, which also limits treatment options; consequently, new therapies are required. The oncoprotein tyr...
Autores principales: | Fan, Gaofeng, Zhang, Siwei, Gao, Yan, Greer, Peter A., Tonks, Nicholas K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949327/ https://www.ncbi.nlm.nih.gov/pubmed/27401557 http://dx.doi.org/10.1101/gad.284166.116 |
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