Toward the mechanism of eIF4F-mediated ribosomal attachment to mammalian capped mRNAs

Ribosomal attachment to mammalian capped mRNAs is achieved through the cap–eukaryotic initiation factor 4E (eIF4E)–eIF4G–eIF3–40S chain of interactions, but the mechanism by which mRNA enters the mRNA-binding channel of the 40S subunit remains unknown. To investigate this process, we recapitulated i...

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Detalles Bibliográficos
Autores principales: Kumar, Parimal, Hellen, Christopher U.T., Pestova, Tatyana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949329/
https://www.ncbi.nlm.nih.gov/pubmed/27401559
http://dx.doi.org/10.1101/gad.282418.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949329/
https://www.ncbi.nlm.nih.gov/pubmed/27401559
http://dx.doi.org/10.1101/gad.282418.116

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