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Preclinical properties and human in vivo assessment of (123) I-ABC577 as a novel SPECT agent for imaging amyloid-β

Non-invasive imaging of amyloid-β in the brain, a hallmark of Alzheimer’s disease, may support earlier and more accurate diagnosis of the disease. In this study, we assessed the novel single photon emission computed tomography tracer (123) I-ABC577 as a potential imaging biomarker for amyloid-β in t...

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Detalles Bibliográficos
Autores principales: Maya, Yoshifumi, Okumura, Yuki, Kobayashi, Ryohei, Onishi, Takako, Shoyama, Yoshinari, Barret, Olivier, Alagille, David, Jennings, Danna, Marek, Kenneth, Seibyl, John, Tamagnan, Gilles, Tanaka, Akihiro, Shirakami, Yoshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949387/
https://www.ncbi.nlm.nih.gov/pubmed/26490333
http://dx.doi.org/10.1093/brain/awv305