Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation

Plasticity in epithelial tissues relates to processes of embryonic development, tissue fibrosis and cancer progression. Pharmacological modulation of epithelial transitions during disease progression may thus be clinically useful. Using human keratinocytes and a robotic high-content imaging platform...

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Detalles Bibliográficos
Autores principales: Carthy, Jon M., Stöter, Martin, Bellomo, Claudia, Vanlandewijck, Michael, Heldin, Angelos, Morén, Anita, Kardassis, Dimitris, Gahman, Timothy C., Shiau, Andrew K., Bickle, Marc, Zerial, Marino, Heldin, Carl-Henrik, Moustakas, Aristidis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949434/
https://www.ncbi.nlm.nih.gov/pubmed/27430378
http://dx.doi.org/10.1038/srep29868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949434/
https://www.ncbi.nlm.nih.gov/pubmed/27430378
http://dx.doi.org/10.1038/srep29868

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