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Discrete somatic niches coordinate proliferation and migration of primordial germ cells via Wnt signaling
Inheritance depends on the expansion of a small number of primordial germ cells (PGCs) in the early embryo. Proliferation of mammalian PGCs is concurrent with their movement through changing microenvironments; however, mechanisms coordinating these conflicting processes remain unclear. Here, we find...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949447/ https://www.ncbi.nlm.nih.gov/pubmed/27402951 http://dx.doi.org/10.1083/jcb.201511061 |