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Discrete somatic niches coordinate proliferation and migration of primordial germ cells via Wnt signaling

Inheritance depends on the expansion of a small number of primordial germ cells (PGCs) in the early embryo. Proliferation of mammalian PGCs is concurrent with their movement through changing microenvironments; however, mechanisms coordinating these conflicting processes remain unclear. Here, we find...

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Detalles Bibliográficos
Autores principales: Cantú, Andrea V., Altshuler-Keylin, Svetlana, Laird, Diana J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949447/
https://www.ncbi.nlm.nih.gov/pubmed/27402951
http://dx.doi.org/10.1083/jcb.201511061