Cortactin promotes exosome secretion by controlling branched actin dynamics

Exosomes are extracellular vesicles that influence cellular behavior and enhance cancer aggressiveness by carrying bioactive molecules. The mechanisms that regulate exosome secretion are poorly understood. Here, we show that the actin cytoskeletal regulatory protein cortactin promotes exosome secret...

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Detalles Bibliográficos
Autores principales: Sinha, Seema, Hoshino, Daisuke, Hong, Nan Hyung, Kirkbride, Kellye C., Grega-Larson, Nathan E., Seiki, Motoharu, Tyska, Matthew J., Weaver, Alissa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949450/
https://www.ncbi.nlm.nih.gov/pubmed/27402952
http://dx.doi.org/10.1083/jcb.201601025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949450/
https://www.ncbi.nlm.nih.gov/pubmed/27402952
http://dx.doi.org/10.1083/jcb.201601025

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