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The anabolic action of intermittent parathyroid hormone on cortical bone depends partly on its ability to induce nitric oxide‐mediated vasorelaxation in BALB/c mice

There is strong evidence that vasodilatory nitric oxide (NO) donors have anabolic effects on bone in humans. Parathyroid hormone (PTH), the only osteoanabolic drug currently approved, is also a vasodilator. We investigated whether the NO synthase inhibitor L‐NAME might alter the effect of PTH on bon...

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Detalles Bibliográficos
Autores principales: Gohin, S, Carriero, A, Chenu, C, Pitsillides, AA, Arnett, TR, Marenzana, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949522/
https://www.ncbi.nlm.nih.gov/pubmed/26834008
http://dx.doi.org/10.1002/cbf.3164