Subtle Structural Differences Trigger Inhibitory Activity of Propafenone Analogues at the Two Polyspecific ABC Transporters: P‐Glycoprotein (P‐gp) and Breast Cancer Resistance Protein (BCRP)

The transmembrane ABC transporters P‐glycoprotein (P‐gp) and breast cancer resistance protein (BCRP) are widely recognized for their role in cancer multidrug resistance and absorption and distribution of compounds. Furthermore, they are linked to drug–drug interactions and toxicity. Nevertheless, du...

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Detalles Bibliográficos
Autores principales: Schwarz, Theresa, Montanari, Floriane, Cseke, Anna, Wlcek, Katrin, Visvader, Lene, Palme, Sarah, Chiba, Peter, Kuchler, Karl, Urban, Ernst, Ecker, Gerhard F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949556/
https://www.ncbi.nlm.nih.gov/pubmed/26970257
http://dx.doi.org/10.1002/cmdc.201500592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949556/
https://www.ncbi.nlm.nih.gov/pubmed/26970257
http://dx.doi.org/10.1002/cmdc.201500592

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