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Associations between polygenic risk for schizophrenia and brain function during probabilistic learning in healthy individuals

A substantial proportion of schizophrenia liability can be explained by additive genetic factors. Risk profile scores (RPS) directly index risk using a summated total of common risk variants weighted by their effect. Previous studies suggest that schizophrenia RPS predict alterations to neural netwo...

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Detalles Bibliográficos
Autores principales: Lancaster, Thomas M., Ihssen, Niklas, Brindley, Lisa M., Tansey, Katherine E., Mantripragada, Kiran, O'Donovan, Michael C., Owen, Michael J., Linden, David E.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949629/
https://www.ncbi.nlm.nih.gov/pubmed/26510167
http://dx.doi.org/10.1002/hbm.23044