The anticonvulsant retigabine is a subtype selective modulator of GABA (A) receptors

OBJECTIVE: Within its range of therapeutic plasma concentrations, the anticonvulsant retigabine (ezogabine) is believed to selectively act on Kv7 channels. Here, the contribution of specific γ‐aminobutyric acid (GABA)(A) receptor subtypes to the antiseizure effects of retigabine was investigated. ME...

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Detalles Bibliográficos
Autores principales: Treven, Marco, Koenig, Xaver, Assadpour, Elham, Gantumur, Enkhbileg, Meyer, Christiane, Hilber, Karlheinz, Boehm, Stefan, Kubista, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Full‐length Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949651/
https://www.ncbi.nlm.nih.gov/pubmed/25779225
http://dx.doi.org/10.1111/epi.12950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949651/
https://www.ncbi.nlm.nih.gov/pubmed/25779225
http://dx.doi.org/10.1111/epi.12950

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