Cargando…
The anticonvulsant retigabine is a subtype selective modulator of GABA (A) receptors
OBJECTIVE: Within its range of therapeutic plasma concentrations, the anticonvulsant retigabine (ezogabine) is believed to selectively act on Kv7 channels. Here, the contribution of specific γ‐aminobutyric acid (GABA)(A) receptor subtypes to the antiseizure effects of retigabine was investigated. ME...
Autores principales: | Treven, Marco, Koenig, Xaver, Assadpour, Elham, Gantumur, Enkhbileg, Meyer, Christiane, Hilber, Karlheinz, Boehm, Stefan, Kubista, Helmut |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949651/ https://www.ncbi.nlm.nih.gov/pubmed/25779225 http://dx.doi.org/10.1111/epi.12950 |
Ejemplares similares
-
Calcium current properties in dystrophin‐deficient ventricular cardiomyocytes from aged mdx mice
por: Rubi, Lena, et al.
Publicado: (2018) -
Decreased inward rectifier potassium current I(K1) in dystrophin-deficient ventricular cardiomyocytes
por: Rubi, Lena, et al.
Publicado: (2016) -
Psilocybin Therapy of Psychiatric Disorders Is Not Hampered by hERG Potassium Channel–Mediated Cardiotoxicity
por: Hackl, Benjamin, et al.
Publicado: (2021) -
The anticonvulsant retigabine suppresses neuronal K(V)2-mediated currents
por: Stas, Jeroen I., et al.
Publicado: (2016) -
Antiepileptic activity and subtype-selective action of flupirtine at GABA(A) receptors
por: Bajrić, Mirnes, et al.
Publicado: (2012)