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Identification of clinical target areas in the brainstem of prion‐infected mice

AIMS: While prion infection ultimately involves the entire brain, it has long been thought that the abrupt clinical onset and rapid neurological decline in laboratory rodents relates to involvement of specific critical neuroanatomical target areas. The severity and type of clinical signs, together w...

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Detalles Bibliográficos
Autores principales: Mirabile, Ilaria, Jat, Parmjit S., Brandner, Sebastian, Collinge, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949711/
https://www.ncbi.nlm.nih.gov/pubmed/25311251
http://dx.doi.org/10.1111/nan.12189