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Mycolic acids: deciphering and targeting the Achilles' heel of the tubercle bacillus

Mycolic acids are unique long chain fatty acids found in the lipid‐rich cell walls of mycobacteria including the tubercle bacillus M ycobacterium tuberculosis. Essential for viability and virulence, enzymes involved in the biosynthesis of mycolic acids represent novel targets for drug development. T...

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Detalles Bibliográficos
Autores principales: Nataraj, Vijayashankar, Varela, Cristian, Javid, Asma, Singh, Albel, Besra, Gurdyal S., Bhatt, Apoorva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949712/
https://www.ncbi.nlm.nih.gov/pubmed/26135034
http://dx.doi.org/10.1111/mmi.13101