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Mycolic acids: deciphering and targeting the Achilles' heel of the tubercle bacillus
Mycolic acids are unique long chain fatty acids found in the lipid‐rich cell walls of mycobacteria including the tubercle bacillus M ycobacterium tuberculosis. Essential for viability and virulence, enzymes involved in the biosynthesis of mycolic acids represent novel targets for drug development. T...
Autores principales: | Nataraj, Vijayashankar, Varela, Cristian, Javid, Asma, Singh, Albel, Besra, Gurdyal S., Bhatt, Apoorva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949712/ https://www.ncbi.nlm.nih.gov/pubmed/26135034 http://dx.doi.org/10.1111/mmi.13101 |
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