Identification of V-ATPase as a molecular sensor of SOX11-levels and potential therapeutic target for mantle cell lymphoma

BACKGROUND: Mantle cell lymphoma (MCL) is an aggressive disease with short median survival. Molecularly, MCL is defined by the t(11;14) translocation leading to overexpression of the CCND1 gene. However, recent data show that the neural transcription factor SOX11 is a disease defining antigen and se...

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Detalles Bibliográficos
Autores principales: Emruli, Venera Kuci, Olsson, Roger, Ek, Fredrik, Ek, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949756/
https://www.ncbi.nlm.nih.gov/pubmed/27430213
http://dx.doi.org/10.1186/s12885-016-2550-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949756/
https://www.ncbi.nlm.nih.gov/pubmed/27430213
http://dx.doi.org/10.1186/s12885-016-2550-4

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