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Pilot Randomized trial of Fibrinogen in Trauma Haemorrhage (PRooF-iTH): study protocol for a randomized controlled trial

BACKGROUND: Haemorrhage remains a leading cause of morbidity and mortality in trauma patients. Fibrinogen is an essential endogenous component of haemostasis and the plasma level is associated with bleeding, transfusion and outcome. Fibrinogen concentrate is widely used to correct acquired hypofibri...

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Detalles Bibliográficos
Autores principales: Steinmetz, Jacob, Sørensen, Anne Marie, Henriksen, Hanne Hee, Lange, Theis, Larsen, Claus Falck, Johansson, Pär I., Stensballe, Jakob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949907/
https://www.ncbi.nlm.nih.gov/pubmed/27430210
http://dx.doi.org/10.1186/s13063-016-1439-5