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Transcription of Leishmania major U2 small nuclear RNA gene is directed by extragenic sequences located within a tRNA-like and a tRNA-Ala gene

BACKGROUND: Leishmania and other trypanosomatid parasites possess atypical mechanisms of gene expression, including the maturation of mRNAs by trans-splicing and the involvement of RNA Polymerase III in transcription of all snRNA molecules. Since snRNAs are essential for trans-splicing, we are inter...

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Detalles Bibliográficos
Autores principales: Rojas-Sánchez, Saúl, Figueroa-Angulo, Elisa, Moreno-Campos, Rodrigo, Florencio-Martínez, Luis E., Manning-Cela, Rebeca G., Martínez-Calvillo, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950102/
https://www.ncbi.nlm.nih.gov/pubmed/27430335
http://dx.doi.org/10.1186/s13071-016-1682-3