Kinetic and structural characterization of amyloid‐β peptide hydrolysis by human angiotensin‐1‐converting enzyme

Angiotensin‐1‐converting enzyme (ACE), a zinc metallopeptidase, consists of two homologous catalytic domains (N and C) with different substrate specificities. Here we report kinetic parameters of five different forms of human ACE with various amyloid beta (Aβ) substrates together with high resolutio...

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Detalles Bibliográficos
Autores principales: Larmuth, Kate M., Masuyer, Geoffrey, Douglas, Ross G., Schwager, Sylva L., Acharya, K. Ravi, Sturrock, Edward D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950319/
https://www.ncbi.nlm.nih.gov/pubmed/26748546
http://dx.doi.org/10.1111/febs.13647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950319/
https://www.ncbi.nlm.nih.gov/pubmed/26748546
http://dx.doi.org/10.1111/febs.13647

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