Modulating myosin restores muscle function in a mouse model of nemaline myopathy

OBJECTIVE: Nemaline myopathy, one of the most common congenital myopathies, is associated with mutations in various genes including ACTA1. This disease is also characterized by various forms/degrees of muscle weakness, with most cases being severe and resulting in death in infancy. Recent findings h...

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Detalles Bibliográficos
Autores principales: Lindqvist, Johan, Levy, Yotam, Pati‐Alam, Alisha, Hardeman, Edna C., Gregorevic, Paul, Ochala, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950341/
https://www.ncbi.nlm.nih.gov/pubmed/26891371
http://dx.doi.org/10.1002/ana.24619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950341/
https://www.ncbi.nlm.nih.gov/pubmed/26891371
http://dx.doi.org/10.1002/ana.24619

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