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Na(v)1.7 and other voltage-gated sodium channels as drug targets for pain relief

Introduction: Chronic pain is a massive clinical problem. We discuss the potential of subtype selective sodium channel blockers that may provide analgesia with limited side effects. Areas covered: Sodium channel subtypes have been linked to human pain syndromes through genetic studies. Gain of funct...

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Detalles Bibliográficos
Autores principales: Emery, Edward C, Luiz, Ana Paula, Wood, John N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950419/
https://www.ncbi.nlm.nih.gov/pubmed/26941184
http://dx.doi.org/10.1517/14728222.2016.1162295