Cargando…

HPV16 E6 upregulates Aurora A expression

Overexpression of Aurora A kinase occurs in certain types of cancer, and therefore results in chromosome instability and phosphorylation-mediated ubiquitylation and degradation of p53 for tumorigenesis. The high-risk subtype human papillomavirus (HPV)16 early oncoprotein E6 is a major contributor in...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Yi, Ma, Jiaming, Zheng, Yahong, Li, Lu, Gui, Xiaowei, Wang, Qian, Meng, Xiangkai, Shang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950527/
https://www.ncbi.nlm.nih.gov/pubmed/27446442
http://dx.doi.org/10.3892/ol.2016.4786