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Association between aberrant APC promoter methylation and breast cancer pathogenesis: a meta-analysis of 35 observational studies

Background. Adenomatous polyposis coli (APC) is widely known as an antagonist of the Wnt signaling pathway via the inactivation of β-catenin. An increasing number of studies have reported that APC methylation contributes to the predisposition to breast cancer (BC). However, recent studies have yield...

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Detalles Bibliográficos
Autores principales: Zhou, Dan, Tang, Weiwei, Wang, Wenyi, Pan, Xiaoyan, An, Han-Xiang, Zhang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950556/
https://www.ncbi.nlm.nih.gov/pubmed/27478702
http://dx.doi.org/10.7717/peerj.2203