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Studying epigenetic complexes and their inhibitors with the proteomics toolbox

Some epigenetic modifier proteins have become validated clinical targets. With a few small molecule inhibitors already approved by national health administrations and many more in the pharmaceutical industry pipelines, there is a need for technologies that can promote full comprehension of the molec...

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Detalles Bibliográficos
Autores principales: Weigt, David, Hopf, Carsten, Médard, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950666/
https://www.ncbi.nlm.nih.gov/pubmed/27437033
http://dx.doi.org/10.1186/s13148-016-0244-z