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BAT117213: Ileal bile acid transporter (IBAT) inhibition as a treatment for pruritus in primary biliary cirrhosis: study protocol for a randomised controlled trial

BACKGROUND: Pruritus (itch) is a symptom commonly experienced by patients with cholestatic liver diseases such as primary biliary cholangitis (PBC, previously referred to as primary biliary cirrhosis). Bile acids (BAs) have been proposed as potential pruritogens in PBC. The ileal bile acid transport...

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Detalles Bibliográficos
Autores principales: Hegade, Vinod S., Kendrick, Stuart F. W., Dobbins, Robert L., Miller, Sam R., Richards, Duncan, Storey, James, Dukes, George, Gilchrist, Kim, Vallow, Susan, Alexander, Graeme J., Corrigan, Margaret, Hirschfield, Gideon M., Jones, David E. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950723/
https://www.ncbi.nlm.nih.gov/pubmed/27431238
http://dx.doi.org/10.1186/s12876-016-0481-9