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Next-generation sequencing methylation profiling of subjects with obesity identifies novel gene changes

BACKGROUND: Obesity is a metabolic disease caused by environmental and genetic factors. However, the epigenetic mechanisms of obesity are incompletely understood. The aim of our study was to investigate the role of skeletal muscle DNA methylation in combination with transcriptomic changes in obesity...

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Detalles Bibliográficos
Autores principales: Day, Samantha E., Coletta, Richard L., Kim, Joon Young, Campbell, Latoya E., Benjamin, Tonya R., Roust, Lori R., De Filippis, Elena A., Dinu, Valentin, Shaibi, Gabriel Q., Mandarino, Lawrence J., Coletta, Dawn K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950754/
https://www.ncbi.nlm.nih.gov/pubmed/27437034
http://dx.doi.org/10.1186/s13148-016-0246-x