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Next-generation sequencing methylation profiling of subjects with obesity identifies novel gene changes
BACKGROUND: Obesity is a metabolic disease caused by environmental and genetic factors. However, the epigenetic mechanisms of obesity are incompletely understood. The aim of our study was to investigate the role of skeletal muscle DNA methylation in combination with transcriptomic changes in obesity...
Autores principales: | Day, Samantha E., Coletta, Richard L., Kim, Joon Young, Campbell, Latoya E., Benjamin, Tonya R., Roust, Lori R., De Filippis, Elena A., Dinu, Valentin, Shaibi, Gabriel Q., Mandarino, Lawrence J., Coletta, Dawn K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950754/ https://www.ncbi.nlm.nih.gov/pubmed/27437034 http://dx.doi.org/10.1186/s13148-016-0246-x |
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