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NLRC5, a promising new entry in tumor immunology

The recent use of T cell-based cancer immunotherapies, such as adoptive T-cell transfer and checkpoint blockade, yields increasing clinical benefit to patients with different cancer types. However, decrease of MHC class I expression is a common mechanism transformed cells take advantage of to evade...

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Detalles Bibliográficos
Autores principales: Chelbi, Sonia T., Guarda, Greta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950760/
https://www.ncbi.nlm.nih.gov/pubmed/27437103
http://dx.doi.org/10.1186/s40425-016-0143-z