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Airway smooth muscle NOX4 is upregulated and modulates ROS generation in COPD

The burden of oxidative stress is increased in chronic obstructive pulmonary disease (COPD). However, whether the intra-cellular mechanisms controlling the oxidant/anti-oxidant balance in structural airway cells such as airway smooth muscle in COPD is altered is unclear. We sought to determine wheth...

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Detalles Bibliográficos
Autores principales: Hollins, Fay, Sutcliffe, Amanda, Gomez, Edith, Berair, Rachid, Russell, Richard, Szyndralewiez, Cédric, Saunders, Ruth, Brightling, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950777/
https://www.ncbi.nlm.nih.gov/pubmed/27435477
http://dx.doi.org/10.1186/s12931-016-0403-y