Proposed Mode of Binding and Action of Positive Allosteric Modulators at Opioid Receptors

[Image: see text] Available crystal structures of opioid receptors provide a high-resolution picture of ligand binding at the primary (“orthosteric”) site, that is, the site targeted by endogenous ligands. Recently, positive allosteric modulators of opioid receptors have also been discovered, but th...

Descripción completa

Detalles Bibliográficos
Autores principales: Shang, Yi, Yeatman, Holly R., Provasi, Davide, Alt, Andrew, Christopoulos, Arthur, Canals, Meritxell, Filizola, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950826/
https://www.ncbi.nlm.nih.gov/pubmed/26841170
http://dx.doi.org/10.1021/acschembio.5b00712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950826/
https://www.ncbi.nlm.nih.gov/pubmed/26841170
http://dx.doi.org/10.1021/acschembio.5b00712

Ejemplares similares