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Fasudil inhibits LPS-induced migration of retinal microglial cells via regulating p38-MAPK signaling pathway

PURPOSE: To investigate the effect and possible molecular mechanisms of fasudil on retinal microglial (RMG) cell migration. METHODS: Primary cultured RMG cells were incubated with lipopolysaccharide (LPS), fasudil, and/or SB203580 (a p38 inhibitor). RMG cell motility was determined with the scratch...

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Detalles Bibliográficos
Autores principales: Xu, Fan, Xu, Yue, Zhu, Liqiong, Rao, Pinhong, Wen, Jiamin, Sang, Yunyun, Shang, Fu, Liu, Yizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2016
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951004/
https://www.ncbi.nlm.nih.gov/pubmed/27441000