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Pyruvate kinase M2 overexpression and poor prognosis in solid tumors of digestive system: evidence from 16 cohort studies

PURPOSE: The expression of pyruvate kinase M2 (PKM2) has been linked to tumor formation and invasion. Specifically, the relationship between high PKM2 expression and prognosis has been evaluated in solid tumors of digestive system. However, the prognostic value of PKM2 remains controversial. METHODS...

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Detalles Bibliográficos
Autores principales: Wu, Jiayuan, Hu, Liren, Chen, Manyu, Cao, Wenjun, Chen, Haicong, He, Taiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951066/
https://www.ncbi.nlm.nih.gov/pubmed/27478385
http://dx.doi.org/10.2147/OTT.S106508