Metal Homeostasis Regulators Suppress FRDA Phenotypes in a Drosophila Model of the Disease

Friedreich’s ataxia (FRDA), the most commonly inherited ataxia in populations of European origin, is a neurodegenerative disorder caused by a decrease in frataxin levels. One of the hallmarks of the disease is the accumulation of iron in several tissues including the brain, and frataxin has been pro...

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Detalles Bibliográficos
Autores principales: Soriano, Sirena, Calap-Quintana, Pablo, Llorens, José Vicente, Al-Ramahi, Ismael, Gutiérrez, Lucía, Martínez-Sebastián, María José, Botas, Juan, Moltó, María Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951068/
https://www.ncbi.nlm.nih.gov/pubmed/27433942
http://dx.doi.org/10.1371/journal.pone.0159209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951068/
https://www.ncbi.nlm.nih.gov/pubmed/27433942
http://dx.doi.org/10.1371/journal.pone.0159209

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