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Metal Homeostasis Regulators Suppress FRDA Phenotypes in a Drosophila Model of the Disease
Friedreich’s ataxia (FRDA), the most commonly inherited ataxia in populations of European origin, is a neurodegenerative disorder caused by a decrease in frataxin levels. One of the hallmarks of the disease is the accumulation of iron in several tissues including the brain, and frataxin has been pro...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951068/ https://www.ncbi.nlm.nih.gov/pubmed/27433942 http://dx.doi.org/10.1371/journal.pone.0159209 |