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Selective Impairment of T(H)17-Differentiation and Protection against Autoimmune Arthritis after Overexpression of BCL2A1 in T Lymphocytes

The inhibition of apoptotic cell death in T cells through the dysregulated expression of BCL2 family members has been associated with the protection against the development of different autoimmune diseases. However, multiple mechanisms were proposed to be responsible for such protective effect. The...

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Detalles Bibliográficos
Autores principales: Iglesias, Marcos, Augustin, Juan Jesús, Alvarez, Pilar, Santiuste, Inés, Postigo, Jorge, Merino, Jesús, Merino, Ramón
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951111/
https://www.ncbi.nlm.nih.gov/pubmed/27433938
http://dx.doi.org/10.1371/journal.pone.0159714