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Dendrimer-Based Selective Proteostasis-Inhibition Strategy to Control NSCLC Growth and Progression

Elevated valosin containing protein (VCP/p97) levels promote the progression of non-small cell lung carcinoma (NSCLC). Although many VCP inhibitors are available, most of these therapeutic compounds have low specificity for targeted tumor cell delivery. Hence, the primary aim of this study was to ev...

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Detalles Bibliográficos
Autores principales: Walworth, Kyla, Bodas, Manish, Campbell, Ryan John, Swanson, Doug, Sharma, Ajit, Vij, Neeraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951140/
https://www.ncbi.nlm.nih.gov/pubmed/27434122
http://dx.doi.org/10.1371/journal.pone.0158507